Anti-NP IgG1/IgG2a Ab ratios in IFN-?/? mice were significantly higher than the ratios determined in WT mice (Fig
Anti-NP IgG1/IgG2a Ab ratios in IFN-?/? mice were significantly higher than the ratios determined in WT mice (Fig. nucleoprotein in IFN-?/? mice did not differ significantly from those in immunocompetent mice. These results indicate that lack of IFN- does not impair cross-reactive virus-specific immune responses and HSI to lethal infection with influenza virus. Our findings… Read More »