As noted in earlier studies,23,30 cells transfected with TFC186S, TFC209S, or TFC186S/C209S exhibited low TF procoagulant activity, approximately 1% or less compared with cells expressing wild-type TF (Physique 2A)
As noted in earlier studies,23,30 cells transfected with TFC186S, TFC209S, or TFC186S/C209S exhibited low TF procoagulant activity, approximately 1% or less compared with cells expressing wild-type TF (Physique 2A). FVIIa, and TF de-encryption does not require Cys186-Cys209 disulfide bond formation. Introduction Tissue factor (TF), a plasma membrane glycoprotein, plays a key role in the initiation… Read More »