The canonical pathway (mediated by Wnt1-3) mediates growth and regeneration and is reported activated in well differentiated HCC cells while it is repressed in poorly differentiated HCC cell lines (41,43,49)
The canonical pathway (mediated by Wnt1-3) mediates growth and regeneration and is reported activated in well differentiated HCC cells while it is repressed in poorly differentiated HCC cell lines (41,43,49). in case of hepatocyte injury, activation of the canonical Wnt pathway, probably helps prevent activation of the Notch pathway, thus pushing LPC differentiation towards hepatocytes… Read More: The canonical pathway (mediated by Wnt1-3) mediates growth and regeneration… »